GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs950169 | 1 | rs12915234 | chr15:84758301 | LOC388152 | chr15:84867600-84898920:- | -0.27 | -4.66 | 4.31E-6 | Schizophrenia |
| BLCA | cis | rs950169 | 1 | rs12916348 | chr15:84765527 | LOC388152 | chr15:84867600-84898920:- | -0.27 | -4.65 | 4.65E-6 | Schizophrenia |
| BLCA | cis | rs9894429 | 1 | rs12948099 | chr17:79600799 | TSPAN10 | chr17:79609349-79615778:+ | 0.48 | 8.34 | 1.34E-15 | Eye color traits |
| BLCA | cis | rs846858 | 1 | rs12975854 | chr19:45120592 | ZNF235 | chr19:44732357-44809178:- | -0.22 | -3.85 | 0.00014 | Late-onset Alzheimer's disease |
| BLCA | cis | rs7246967 | 1 | rs12980225 | chr19:23026745 | ZNF492 | chr19:22817126-22850472:+ | -0.29 | -3.97 | 8.62E-5 | Bronchopulmonary dysplasia |
| BLCA | cis | rs12608504 | 1 | rs12980403 | chr19:18398139 | KIAA1683 | chr19:18367906-18385319:- | -0.24 | -4.38 | 1.56E-5 | Waist-to-hip ratio adjusted for body mass index |
| BLCA | cis | rs7246967 | 1 | rs12983770 | chr19:23023614 | ZNF492 | chr19:22817126-22850472:+ | -0.29 | -3.97 | 8.62E-5 | Bronchopulmonary dysplasia |
| BLCA | cis | rs6708331 | 1 | rs12999430 | chr2:70306785 | FAM136A | chr2:70523109-70529220:- | -0.26 | -4.22 | 3.01E-5 | Obesity-related traits |
| BLCA | cis | rs6708331 | 1 | rs13000817 | chr2:70273707 | FAM136A | chr2:70523109-70529220:- | -0.27 | -4.28 | 2.4E-5 | Obesity-related traits |
| BLCA | cis | rs13004237 | 1 | rs13004237 | chr2:172833139 | MAP1D | chr2:172864804-172945586:+ | -0.28 | -4.95 | 1.1E-6 | Schizophrenia |
| BLCA | cis | rs4663866 | 1 | rs13026475 | chr2:239178455 | LOC151174 | chr2:239133754-239140318:- | 0.46 | 4.51 | 8.67E-6 | Irritable bowel syndrome |
| BLCA | cis | rs6547741 | 1 | rs13026621 | chr2:27807624 | C2orf16 | chr2:27799389-27805588:+ | 0.22 | 3.86 | 0.000135 | Oral cavity cancer |
| BLCA | cis | rs4663866 | 1 | rs13033501 | chr2:239181860 | LOC151174 | chr2:239133754-239140318:- | 0.45 | 4.55 | 7.1E-6 | Irritable bowel syndrome |
| BLCA | cis | rs13053817 | 1 | rs13053758 | chr22:29855489 | MTMR3 | chr22:30279158-30426855:+ | 0.25 | 3.94 | 9.79E-5 | Carotid atherosclerosis in HIV infection |
| BLCA | cis | rs13053817 | 1 | rs13053758 | chr22:29855489 | NIPSNAP1 | chr22:29950800-29977144:- | 0.28 | 3.88 | 0.000125 | Carotid atherosclerosis in HIV infection |